Safety data sheet ghs product identifier synonyms emergency telephone number with hours of operation section 1. Citgo petroleum corporation 5th and new avenue lemont, il 60439 benzene code. Determination of mandelic acid in urine has been recommended as a biomarker of exposure to ethylbenzene. Sigmaaldrich material safety data sheet date printed.
Ethylbenzene is a constituent 1520% of commercial xylene mixed xylenes. Ethylbenzene is used primarily to make another chemical, styrene. Ethylbenzene msds material safety data sheet or sds, coa and coq, dossiers, brochures. Of the methods described, the direct gas chromatographic resolution of the enantiomers on a chiral stationary phase was the best approach.
Sometimes older children sniff household chemicals, including ethylbenzene, in an attempt to get high. Possibly carcinogenic to humans ethylbenzene reproductive toxicity no data available no data available specific target organ toxicity single exposure no data available specific target organ toxicity repeated exposure no data available aspiration hazard may be fatal if swallowed and enters airways. Fact sheets toxfaqs provide answers to frequently asked questions about toxic substances. Product and company identification product name ethylbenzene cat no. Health information summary ethylbenzene is a clear, flammable liquid with a gasolinelike odor. Stereochemical considerations in the metabolism of ethylbenzene and styrene were investigated. The btex mix ture contained benzene, toluene, ethylbenzene, pxy. Ethylene reacts with ethylbenzene to form undesired product di ethyl benzene, if the temperatures of reactor or concentrations of ethylene are high. Styrene is the precursor to polystyrene and several.
We expect you to follow the precautions identified in this. Toxicological profiles are revised and republished as necessary, but no less than once every three years. Find msds or sds, a coa, data sheets and more information. It is to be used during training as an example of what a new safety data sheet will look like under the new hazard communication standard requirements. This edition supersedes any previously released draft or final profile. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet. Styrene, also known as ethenylbenzene, vinylbenzene, and phenylethene, is an organic compound with the chemical formula c 6 h 5 chch 2. The compound evaporates easily and has a sweet smell, although high concentrations have a less pleasant odor. Skin contact wash off immediately with plenty of water for at least 15 minutes. Confirmed animal carcinogen with unknown relevance to humans polar solvent. Airgas usa, llc and its affiliates 259 north radnorchester road suite 100 radnor, pa 190875283. Pocket guide to chemical hazards components type value ethylbenzene cas stel 545 mgm3 100414 125 ppm twa 435 mgm3 100 ppm xylene o, m, p isomers stel 655 mgm3 cas 30207 150 ppm twa 435 mgm3 100 ppm biological limit. Not classifiable as a human carcinogen xylene mixture of isomers iarcgr.
The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. This process involves the reaction of benzene with ethylene to form ethylbenzene. The information in cameo chemicals comes from a variety of data sources. Ambient ethylene concentrations can vary, but are typically less than 0. Talk with your children about the dangers of sniffing chemicals. It takes about 3 days for ethylbenzene to be broken down in air into other. Ethylbenzene concentrations in ambient air samples collected in the united states 180. Jan 21, 2015 ethylbenzene is a colorless liquid that smells like gasoline. Classification according to regulation ec no 12722008. Request pdf analysis of benzene, toluene, ethylbenzene and mxylene in biological samples from the general population a method for the determination of benzene, toluene, ethylbenzene and. Conventionally, the production of eb is based on the alkylation of c 6 h 6 with pure c 2 h 4. The work deals with optimization of the process of production of ethylbenzene by liquidphase benzene alkylation. Degradation is somewhat faster under photochemical.
What happens to ethylbenzene when it enters the environment. Each was analyzed using the conditions given in tables 1 to 3 and the amount of each analyte was determined using the calibration data from table 7. Evaluation of health hazards by exposure to ethylbenzene. Water safety data sheet according to federal register vol. Ethylbenzene msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents. Enviroprep in ethylbenzene greater than 30 ml section 2. Three alternative methods used to determine the enantiomeric composition of mandelicacid in urine arising from exposure to styrene or ethylbenzene were described.
Isobutanol has shown positive results in an in vitro test for potential mutagenicity. The predominant photochemical reaction of ethylbenzene in the atmosphere is with hydroxyl radicals. Ethylbenzene is an iarc group 2b carcinogen based on. It is also used in the manufacture of dyes, rubber adhesives, paints and varnishes, as a constituent in asphalt and. It is also used in the manufacture of dyes, rubber adhesives. Bioassay findings are summarized below to expand on those not stated clearly or completely. Ethylbenzene can be determined in biological material blood, subcutaneous fat, plant foliage, fish samples using headspace gas chromatography gc, gc with mass spectrometry, and gc with flame ionization detection who, 1996a. Other uses include as a solvent, in fuels, and to make other chemicals. The information in this material safety data sheet msds is based on data considered.
In white fish muscle tissue samples, levels ranged 2 ethylbenzene. Material safety data sheet bykw 909 version 3 revision date 030120 print date 030420 2 has caused dermatitis. A toxicological profile for ethylbenzene was released in september 1997. Safety data sheet ghs product identifier other means of identification emergency telephone number with hours of operation section 1. Evaluation of health hazards by exposure to ethylbenzene and. A great variety of catalysts have been investigated for the production of c 2 h 4 by the oxidative dehydrogenation of ethane ode in the last decade 2,3. It covers their hazardous properties, classification and labelling, and information on how to use them safely. Ethylbenzene eb is an important intermediate for the production of styrene.
Sigmaaldrich offers a number of ethylbenzene products. Cover with absorbent sheets, spillcontrol pads or pillows. Ethylbenzene moves easily into the air from water and soil. Ethylbenzene is almost exclusively 99% used as an intermediate for the production of styrene monomer. Ethylbenzene november 2007 longterm health effects of exposure to ethylbenzene background and status of ethylbenzene as a toxic air contaminant and its potential carcinogenicity ethylbenzene cas registry number. Acros organics bvba janssen pharmaceuticalaan 3a 2440 geel, belgium.
Possibly carcinogenic to humans polar solvent iarcgr. Hazards identification target organs eyes, skin, respiratory system, central nervous system cns potential health effects acute effects principle routes of exposure eyes may cause irritation. Ethylbenzene is used mainly for the production of styrene. Since toluene, ethylbenzene, and xylene have comparable toxicities jsoh, 2001a. Safety data sheet creation date 06aug2010 revision date 17jan2018 revision number 6 1. Ethyl benzene cas no 100414 material safety data sheet. In one study, ethylbenzene was detected in urban air at a median concentration of 0.
Eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Longterm health effects of exposure to ethylbenzene. Material safety data sheet bykr 605 version 3 revision date 01102011 print date 01112011 10 further information. Precautions to prevent staticinitated fire or explosion during transfer, storage or handling, include but are not limited to these examples. Styrene production from ethylbenzene the following text in this section is taken from 2 shortened and is permitted for personal use only.
It is a highly flammable, colorless liquid with an odor similar to that of gasoline. Styrene via dehydrogenation over nanodiamonds in an oxygenlean environment. Ethylbenzene is a colorless liquid that smells like gasoline. Acetophenone via selection oxidation in the presence of potassium dichromate supported on neutral alumina and using air as the oxidizing agent. Ethyl benzene material safety data sheet 100 41 4 sdsmsds. Bioassay findings are summarized below to expand on those not stated clearly or completely in saghir et al 2010. July 1, 2014 the dow chemical company page 4 of 7 ethylene. Styrene production from ethylbenzene michigan foam. This safety data sheet is written based on the encapsulated substance or mixture in this article. Dispose of in accordance with applicable localmunicipal, stateprovincial and federal regulations. Ethylbenzene cas twa 20 ppm 100414 xylene o, m, p isomers stel 150 ppm cas 30207 twa 100 ppm us.
Male volunteers were exposed to ethylbenzene vapor in an exposure chamber at 435 mgcu m for 4 hours. Nsrl for ethylbenzene of 54 microgramsday for exposure by inhalation and 41 microgramsday for oral exposure. Less than 1 % of the ethylbenzene produced is used as a paint solvent or as an intermediate for the production of diethylbenzene and acetophenone iarc 2000. Environmental releases ethylene emissions from industrial facilities are subject to. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet emergency telephone number chemtreco, inside the usa. Safety data sheet gasoline, unleaded sample please note. Sigmaaldrich material safety data sheet product name. Toxicological profiles are revised and republished as necessary. This is unique source of information on the chemicals manufactured and imported in europe.
A toxicological profile for ethylbenzene, draft for public comment was released in october 2007. For information regarding the update status of previously released profiles, contact atsdr at. Collect in suitable and properly labeled containers. Ingestion of ethanol can increase effects of overexposure to xylene. Ethylbenzene is an organic compound with the formula c6h5ch2ch3. Selected methods for the analysis of ethylbenzene in various matrices are given in table 1. In the past 5 years, we have grown up as a famous fine chemicals supplier in china and we had established stable business relationships with samsung,lg,merck,thermo fisher scientific and so. This msds also covers compounded samples labeled impact polystyrene nxxxxx and nxxxxxx, where x can be any numeric digit. The results indicate that whereas only the renantiomer of mardelic acid was excreted after ethylbenzene exposure, the mandelic acid from styrene was essentially racemic.
Reference to other sections refer to section 8, exposure controls. Ethylbenzene has been evaluated for carcinogenic activity in fischer rats and b6c3f1 mice exposed by inhalation. This derivative of benzene is a colorless oily liquid although aged samples can appear yellowish. Relevant identified uses of the substance or mixture and uses advised against. Phenylethane recommended use laboratory chemicals 2. Not classifiable as a human carcinogen ethylbenzene acgiha32010.
Firstaid measures general advice if symptoms persist, call a physician. Sds of ethylbenzene, safety data sheets, cas 100414. The determination of low levels of benzene, toluene. The general public includes children, the elderly, pregnant women and people with preexisting health conditions. Exposure to benzene, toluene, ethylbenzene, xylene. Industrialgrade xylene meets astm d364 specifications. This monocyclic aromatic hydrocarbon is important in the petrochemical industry as an intermediate in the production of styrene, the precursor to polystyrene, a common plastic material.
Mean concentrations of ethylbenzene found in freshwater fish samples ranged from 2. Ethylbenzene has been evaluated for carcinogenic activity in fischer rats and b6c3f1 mice exposed by inhalation chan et al 1998. Ac140090000, ac140090010, ac140090025, ac140090100, ac140095000 synonyms. Overall in these three studies animals exposed to ethylbenzene. Ethylbenzene may be used as a starting material to synthesize. This material may contain ethyl benzene, cumene and naphthalene at.
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